교수진 및 연구실 소개SAIHST에는 기초의학, 임상의학, 자연과학, 약학, 공학, 경영대학 등 Health Science와 관련된 다양한 분야를 전공한 교수진이 참여하고 있습니다.
미래의과학을 선도할 역량있는 교수의 참여를 기다립니다.
| 연구실소개 |
Molecular & Medical Genomics Laboratory /이지은 교수 E-mail : jieun.lee@skku.edu Homepage : https://jieunleelab.wixsite.com/mmgl 참여학과 : 융합의과학과, 디지털헬스학과 인쇄하기 |
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■ Research objective
Our lab has been interested in understanding biogenesis of the primary cilium and its role in diverse cellular processes and human diseases. The primary cilium, distinct from the motile cilia, is a cellular organelle that protrudes from the cellular membrane. The primary cilium is non-motile and solely exists in most types of eukaryote cells. Mainly, we identify novel genes from patients or focus on unknown genes to investigate the association of the primary cilium with diseases. Our lab has been also interested in generating disease animal model using zebrafish and applying the models to screening and/or development of therapeutic chemicals. ■ Research interests -Role of the primary cilium in metabolic disorders Our lab currently investigates role of the primary cilium in adipogenesis and the effect of its deficit on metabolic disorders including diabetes and obesity. -Role of the primary cilium in myopathies Our lab currently investigates role of the primary cilium in muscle differentiation and the effect of its deficit on myopathies. -Role of the primary cilium in cancer Our lab currently investigates role of the primary cilium in cell cycle regulation, ubiquitin-proteasome system, and mRNA splicing and the effect of its deficit on cancer. ■ Contact jieun.lee@skku.edu |